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GCSE Biology Revision

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GCSE Biology revision

Viral diseases

Communicable diseases

AQA 4.1.1.1
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AQA student objectives

Learning pathway

All ยท Most ยท Some

ALL ๐ŸŽฏ

Identify and describe What Are Viral Diseases?, Measles: Cause and Spread and Measles: Symptoms and Complications in the context of viral diseases.

MOST ๐ŸŽฏ๐ŸŽฏ

Explain the relationships between What Are Viral Diseases?, Measles: Cause and Spread and Measles: Symptoms and Complications and how they contribute to viral diseases.

SOME ๐ŸŽฏ๐ŸŽฏ๐ŸŽฏ

Apply and analyse knowledge of What Are Viral Diseases?, Measles: Cause and Spread and Measles: Symptoms and Complications to interpret unfamiliar information about viral diseases.

Revision summary

Key knowledge

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What Are Viral Diseases?

  • Viral diseases are infections caused by viruses that invade the body's cells and disrupt normal biological processes.
  • Viruses can infect both animals and plants, making them a wide-ranging threat to living organisms.
  • Typically, the three key viral diseases to know about are measles, HIV, and tobacco mosaic virus (TMV).

Measles: Cause and Spread

  • Measles is a viral infection caused by the measles virus.
  • It is spread through droplet infection, meaning the virus travels in tiny droplets of saliva released when an infected person sneezes or coughs.
  • Because it spreads through the air, measles is highly contagious in environments where people are in close contact.

Measles: Symptoms and Complications

  • The main symptoms of measles include a red skin rash, a high fever, and small white spots inside the mouth.
  • A serious complication of measles is encephalitis, which is inflammation of the brain and can be fatal.
  • Deaths from measles have decreased significantly due to the widespread use of the MMR vaccine, which protects against mumps, measles, and rubella.

HIV: What It Is and How It Spreads

  • HIV stands for Human Immunodeficiency Virus, and as the name suggests, it causes a deficiency in the body's immune system.
  • HIV is spread through the exchange of bodily fluids, including unprotected sexual intercourse, sharing needles, and contact between open wounds and infected blood.
  • Preventative measures include using condoms, practising hygienic needle use, and covering open wounds โ€” particularly important for healthcare workers.

HIV: How It Affects the Body

  • HIV attacks and destroys CD4 T cells, which are a type of white blood cell essential for a functioning immune system.
  • Over time, the number of virus particles increases while the number of CD4 T cells decreases, progressively weakening the immune system.
  • When the immune system becomes severely weakened, the condition progresses to AIDS (Acquired Immune Deficiency Syndrome), leaving the patient extremely vulnerable to other infections.
  • Even a common cold can become life-threatening for a person with AIDS due to their severely compromised immunity.

HIV: Treatment and Management

  • There is currently no vaccine or cure for HIV.
  • Antiretroviral drugs are used to control HIV by slowing the replication of the virus, significantly extending the life expectancy of those infected.
  • HIV patients must take extra precautions to avoid other infections, as their weakened immune system struggles to fight off pathogens.

Tobacco Mosaic Virus (TMV): Cause and Spread

  • Tobacco mosaic virus (TMV) is a viral disease that infects tobacco plants and other related species such as tomatoes and peppers.
  • TMV can spread when infected and healthy plants touch one another, or when a farmer handles an infected plant and then touches a healthy one.
  • To prevent the spread of TMV, farmers should keep plants separated, remove infected plants, and wash their hands between handling different plants.

Tobacco Mosaic Virus (TMV): Symptoms and Impact

  • TMV infects the chloroplasts of plant cells, damaging the chlorophyll and causing a characteristic mosaic-like pattern of yellow discolouration on leaves.
  • Because chlorophyll gives plants their green colour and is essential for photosynthesis, its destruction reduces the plant's ability to photosynthesise.
  • Infected leaves may also curl up, reducing the surface area available for light absorption and further limiting photosynthesis.
  • The overall reduction in photosynthesis stunts plant growth and significantly reduces crop yields, making TMV a major concern in agriculture.

Comparing the Three Viral Diseases

  • Measles and HIV are both human viral diseases, but they differ in how they spread โ€” measles via droplets and HIV via bodily fluids.
  • TMV is a plant viral disease, distinguishing it from measles and HIV which affect animals.
  • All three diseases have no complete cure, highlighting the importance of prevention through vaccination (measles), safe practices (HIV), and good hygiene and crop management (TMV).

Exam Tips for Viral Diseases

  • Examiners may show a photograph of mosaic-like yellowing on a plant leaf and ask you to identify the disease โ€” recognising this pattern means it is tobacco mosaic virus.
  • Remember that HIV stands for Human Immunodeficiency Virus; breaking down the name in an exam can help you recall that it weakens the immune system.
  • The three key symptoms of measles โ€” red rash, high fever, and white spots in the mouth โ€” are a common short-answer exam question and should be memorised.
  • Knowing the difference between HIV (the virus) and AIDS (the advanced stage of the disease) is important for picking up marks in longer answer questions.