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GCSE Biology Revision

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GCSE Biology revision

Blood

Animal tissues, organs and organ systems

AQA 4.1.1.1
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AQA student objectives

Learning pathway

All · Most · Some

ALL 🎯

Identify and describe The Four Components of Blood, Red Blood Cells & Haemoglobin and Adaptations of Red Blood Cells in the context of blood.

MOST 🎯🎯

Explain the relationships between The Four Components of Blood, Red Blood Cells & Haemoglobin and Adaptations of Red Blood Cells and how they contribute to blood.

SOME 🎯🎯🎯

Apply and analyse knowledge of The Four Components of Blood, Red Blood Cells & Haemoglobin and Adaptations of Red Blood Cells to interpret unfamiliar information about blood.

Revision summary

Key knowledge

Read on screen, then print for Cornell-style active revision.

The Four Components of Blood

  • Blood is made up of four main components: red blood cells, white blood cells, platelets, and plasma
  • Red blood cells (RBCs) make up almost half of the blood's volume, while white blood cells account for less than 1%
  • Plasma makes up just over half of the blood's volume and is a pale straw-coloured liquid that allows blood to flow

Red Blood Cells & Haemoglobin

  • The role of red blood cells is to carry oxygen from the lungs to the body's tissues for use in cellular respiration
  • Red blood cells contain a red pigment called haemoglobin, which combines with oxygen to form oxyhaemoglobin
  • Once red blood cells reach the body's tissues, oxyhaemoglobin splits back into haemoglobin and oxygen, allowing oxygen to diffuse into the tissues

Adaptations of Red Blood Cells

  • Red blood cells lack a nucleus, which creates more space for haemoglobin and oxygen
  • Red blood cells are shaped like a biconcave disc, which gives them a large surface area for absorbing oxygen

White Blood Cells & the Immune System

  • White blood cells are an essential part of the immune system, defending the body against infection
  • Phagocytosis is the process by which a white blood cell engulfs and consumes a microorganism
  • White blood cells can produce antibodies, which bind to pathogens and help destroy them
  • White blood cells can also produce antitoxins, which neutralise toxins produced by pathogens
  • Unlike red blood cells, white blood cells do contain a nucleus

Platelets & Blood Clotting

  • Platelets are not full cells but small fragments of cells, and therefore do not have a nucleus
  • When a cut occurs, platelets rush to the wound and clot the blood, sealing the hole to prevent blood loss
  • Clotting also prevents microorganisms from entering the wound, reducing the risk of infection

The Role of Plasma

  • Plasma is a pale straw-coloured liquid that carries red blood cells, white blood cells, and platelets throughout the body
  • Plasma transports nutrients such as glucose and amino acids, as well as waste products like carbon dioxide and urea
  • Plasma also carries hormones, proteins, and the antibodies and antitoxins produced by white blood cells

Artificial Blood

  • Artificial blood is a blood substitute that consists mainly of salt water, used to add volume to the circulatory system
  • The main benefit of artificial blood is that it keeps blood vessels full and allows the heart to continue pumping
  • A key limitation is that artificial blood contains no red blood cells, so it cannot transport additional oxygen, meaning only about one-third of blood can be replaced with it

Blood Transfusions

  • A blood transfusion involves giving a patient real donated blood, which contains its own red blood cells
  • Blood transfusions are a more effective option than artificial blood because they restore the body's ability to transport oxygen
  • Blood transfusions are used when a patient has lost too much blood, for example due to a knife wound or surgical complications, and their tissues are not receiving enough oxygen