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GCSE Biology Revision

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GCSE Biology revision

Diffusion

Transport in cells

AQA 4.1.1.1
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AQA student objectives

Learning pathway

All · Most · Some

ALL 🎯

Identify and describe What is Surface Area to Volume Ratio?, Calculating SA:V Ratio Using Cubes and Small Organisms and Diffusion in the context of diffusion.

MOST 🎯🎯

Explain the relationships between What is Surface Area to Volume Ratio?, Calculating SA:V Ratio Using Cubes and Small Organisms and Diffusion and how they contribute to diffusion.

SOME 🎯🎯🎯

Apply and analyse knowledge of What is Surface Area to Volume Ratio?, Calculating SA:V Ratio Using Cubes and Small Organisms and Diffusion to interpret unfamiliar information about diffusion.

Revision summary

Key knowledge

Read on screen, then print for Cornell-style active revision.

What is Surface Area to Volume Ratio?

  • Surface area to volume ratio (SA:V ratio) is a measure comparing the total surface area of an organism to its internal volume
  • The surface area is the outer boundary across which substances can be exchanged, whilst the volume represents all the internal space that needs to be supplied
  • As organisms get larger, their SA:V ratio decreases because volume increases much more rapidly than surface area

Calculating SA:V Ratio Using Cubes

  • The surface area of a cube is calculated by finding the area of one face and multiplying by six: SA = 6 × l²
  • The volume of a cube is calculated by multiplying length × width × height: V = l³
  • A 1 cm cube has a SA:V ratio of 6:1, a 2 cm cube has 3:1, and a 3 cm cube has 2:1, demonstrating that the ratio decreases as size increases
  • In the example above, surface area increases 9 times but volume increases 27 times, showing that volume grows far more quickly than surface area

Small Organisms and Diffusion

  • Bacteria are single-celled organisms with a very high SA:V ratio, meaning they have a large surface area relative to their internal volume
  • Because of their high SA:V ratio, bacteria can rely entirely on diffusion across their cell surface to absorb resources such as oxygen, glucose, and amino acids, and to remove waste products like carbon dioxide
  • Diffusion is sufficient for small organisms because every part of their internal volume is very close to the outer surface

Why Large Organisms Cannot Rely on Simple Diffusion

  • Large multicellular organisms like humans have a low SA:V ratio, meaning their surface area is too small relative to their volume to supply all their cells by diffusion alone
  • As organisms increase in size, diffusion distances increase enormously — for example, a molecule must travel approximately 1 micrometre to reach the centre of a bacterium, but at least 5 cm to reach the centre of a human body
  • This 50,000-fold increase in diffusion distance means diffusion would be far too slow to meet the needs of all cells in a large organism

Specialised Exchange Surfaces in Animals

  • Large organisms have evolved specialised exchange surfaces that effectively increase the SA:V ratio by providing a much greater internal surface area for substance exchange
  • In the lungs, millions of tiny air sacs called alveoli provide an enormous surface area for the exchange of oxygen and carbon dioxide between the air and the blood
  • In the small intestine, finger-like projections called villi provide a massive surface area for the efficient absorption of digested nutrients into the bloodstream

Transport Systems in Large Organisms

  • Because diffusion distances are too great in large organisms, they require specialised transport systems to carry substances from exchange surfaces to individual cells throughout the body
  • In animals, the circulatory system — comprising the heart and blood vessels — transports molecules such as oxygen and glucose around the body
  • Once substances are delivered close to cells by the transport system, they only need to diffuse a very short distance to enter the cells, making the process efficient

Exchange and Transport in Plants

  • Plants also require specialised exchange surfaces and transport systems because they are large enough that diffusion alone cannot supply all their cells
  • Roots and leaves act as exchange surfaces, allowing plants to absorb water, mineral ions, and carbon dioxide from their environment
  • Xylem tissue transports water and mineral ions from the roots up through the plant, whilst phloem tissue transports dissolved sugars and other organic molecules around the plant

The Rule Applies to All Visible Organisms

  • The need for specialised exchange surfaces and transport systems is not limited to large animals like humans and cows — it applies to any organism large enough to be seen with the naked eye
  • Even relatively small animals such as insects like mosquitoes possess exchange surfaces and transport systems to meet the demands of their cells
  • The key principle is that once an organism is too large for simple diffusion to supply all its cells efficiently, specialised systems become necessary for survival

Summary: SA:V Ratio and Biological Complexity

  • Small organisms have a high SA:V ratio and can exchange all necessary substances by diffusion directly across their surface
  • Large organisms have a low SA:V ratio and require specialised exchange surfaces (eg lungs, intestines, roots, leaves) to increase the effective surface area for exchange
  • Large organisms also require transport systems (eg the circulatory system in animals, xylem and phloem in plants) to distribute substances efficiently throughout the body